Top 100 US Patents in Measurement and Sampling
section g - physics > measuring; testing > investigating or analysing materials by determining their chemical or physical properties
Sorted by IPQ® Score, an objective measure of patent quality. View scores and methodology at PatentRatings.com. You can also view all by publication date instead.
US5968760 (A), filed
Fri Nov 07 00:00:00 CST 1997
, published
Tue Oct 19 00:00:00 CDT 1999
- LIFESCAN INC
A method for determining the presence of an analyte in a fluid is described along with various components of an apparatus specifically designed to carry out the method. The method involves taking a reflectance reading from one surface of an inert porous matrix...
US6720166 (B2), filed
Mon Jun 05 00:00:00 CDT 1995
, published
Tue Apr 13 00:00:00 CDT 2004
- ABBOTT LAB
Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to...
US6365033 (B1), filed
Tue Aug 31 00:00:00 CDT 1999
, published
Tue Apr 02 00:00:00 CST 2002
- SEMITOOF INC
A method for measuring a target constituent of an electroplating solution using an electroanalytical technique is set forth in which the electroplating solution includes one or more constituents whose by-products skew an initial electrical response to an...
US7001496 (B2), filed
Wed Dec 18 00:00:00 CST 2002
, published
Tue Feb 21 00:00:00 CST 2006
- CALIPER LIFE SCIENCES INC
A channel ( 140 ) is divised into portions ( 142, 144 ). The sidewalls of each channel portion ( 142, 144 ) have surface charges of opposite polarity. The two channel portions ( 142, 144 ) are physically connected together by a salt bridge ( 133 ), such as a...
US4447340 (A), filed
Tue Jun 22 00:00:00 CDT 1982
, published
Tue May 08 00:00:00 CDT 1984
- PETROLES CIE FRANCAISE
In a method of tracing a well drilling mud by determining the concentration of a tracer ion in samples of filtrate from a drilling mud which contains a predetermined concentration of the tracer ion, the improvement wherein the tracer ion is the acetate ion and...
US4926452 (A), filed
Fri Oct 30 00:00:00 CST 1987
, published
Tue May 15 00:00:00 CDT 1990
- FOUR PI SYSTEMS CORP
A tomographic inspection system wherein the electron beam of a microfocus X-ray tube is deflected in a circular scan pattern onto the tube anode in synchronization with a rotating detector that converts the X-ray shadowgraph into an optical image and derotates...
US4404922 (A), filed
Mon Jul 28 00:00:00 CDT 1980
, published
Tue Sep 20 00:00:00 CDT 1983
- OREAL
An ageing indicator compares a closed sachet of one or more closed tubes of a material which is slightly permeable to a fluid contained in the sachet or tube. The rate of permeation of the fluid through the sachet-like assembly tube wall depends upon...
US6306594 (B1), filed
Tue Nov 17 00:00:00 CST 1998
, published
Tue Oct 23 00:00:00 CDT 2001
- I STAT CORP
An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features...
US4877436 (A), filed
Mon Mar 13 00:00:00 CST 1989
, published
Tue Oct 31 00:00:00 CST 1989
- SHEINKOP ISAC
A method for manufacturing glass comprises forming glass from molten mineral material, continuously discharging an auxiliary stream of molten mineral material, continuously measuring the temperature and the mass flow rate by laser means of the auxiliary...
US6702705 (B1), filed
Wed Feb 22 00:00:00 CST 1995
, published
Tue Mar 09 00:00:00 CST 2004
- IGEN INT INC
Catalytic antibodies are disclosed. The catalytic antibodies are specific for prodrug compounds. The catalytic antibodies enhance cleavage of an active drug moiety from a prodrug residue, thereby activating the drug.
US6650409 (B1), filed
Thu Mar 14 00:00:00 CST 1996
, published
Tue Nov 18 00:00:00 CST 2003
- HITACHI LTD
A semiconductor device producing method and a semiconductor device producing system employs a processing apparatus provided with a dust particle detecting apparatus. The dust particle detecting apparatus measures the condition of adhesion of dust particles...
US5287167 (A), filed
Wed Jul 31 00:00:00 CDT 1991
, published
Tue Feb 15 00:00:00 CST 1994
- TOSHIBA CERAMICS CO
The invention related to a method for determining a silicon wafer in which the interstitial oxygen concentration of a pulled silicon wafer is calculated on the basis of a light transmission characteristic measured by utilizing parallel polarized light incident...
US7314713 (B1), filed
Wed Sep 03 00:00:00 CDT 2003
, published
Tue Jan 01 00:00:00 CST 2008
- MYRIAD GENETICS INC
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human obesity and diabetes predisposing gene, specifically the TBC1D1 gene, some mutant...
US6780613 (B1), filed
Wed Jun 07 00:00:00 CDT 1995
, published
Tue Aug 24 00:00:00 CDT 2004
- GENENTECH INC
The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target substance. Such active domains are determined by substituting...
US4391904 (A), filed
Fri Apr 17 00:00:00 CST 1981
, published
Tue Jul 05 00:00:00 CDT 1983
- SYVA CO
An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) of immunogens-ligand and receptor. The method has two basic elements: a solid surface to which one of...
US6916604 (B2), filed
Fri Mar 07 00:00:00 CST 2003
, published
Tue Jul 12 00:00:00 CDT 2005
- WASHINGTON RES FOUND
Peptides synthesized to match the human alpha1 (I) and alpha2 (I) amino-telopeptide sequences of type I collagen degradation products in body fluids, preferably either Asp-GIu-Lys-Ser-Thr-Gly-Gly (SEQ ID NO:5) or Gln-Tyr-Asp-Gly-Lys-Gly-Val-Gly (SEQ ID NO:6)....
US6725072 (B2), filed
Fri Dec 29 00:00:00 CST 2000
, published
Tue Apr 20 00:00:00 CDT 2004
- HEMA METRICS INC
An optical sensor includes photoemitter and photodetector elements at multiple spacings (d1, d2) for the purpose of measuring the bulk absorptivity (alpha) of an area immediately surrounding and including a hemodialysis access site, and the absorptivity...
US5119684 (A), filed
Thu Jul 26 00:00:00 CDT 1990
, published
Tue Jun 09 00:00:00 CDT 1992
- PIKE DANIEL E
An apparatus for determining the collectability of dust particles is disclosed herein. The concept of collectability and collectivity are employed to establish fundamental equations which are solved by the use of data obtained by passing a dust laden gas...
US5210702 (A), filed
Wed Dec 26 00:00:00 CST 1990
, published
Tue May 11 00:00:00 CDT 1993
- COLORADO SEMINARY
A gas analysis device for the remote detecting, measuring and recording of NOx, CO, CO2, HC and H2O levels from the exhaust of moving motor vehicles. It utilizes a source of collimated infrared and ultraviolet radiation and includes a mechanism for receiving...
US5164598 (A), filed
Tue Feb 05 00:00:00 CST 1991
, published
Tue Nov 17 00:00:00 CST 1992
- BIOTRACK
Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with...
US5118472 (A), filed
Fri Jul 08 00:00:00 CDT 1988
, published
Tue Jun 02 00:00:00 CDT 1992
- FUJI PHOTO FILM CO LTD
US6800617 (B1), filed
Mon Mar 22 00:00:00 CST 1993
, published
Tue Oct 05 00:00:00 CDT 2004
- UNIV JOHNS HOPKINS
Methods are provided for restoring wild-type p53 gene function to a cell. Such methods include gene therapy. Typically, this will stop tumor cells from proliferating.
US5605662 (A), filed
Mon Nov 01 00:00:00 CST 1993
, published
Tue Feb 25 00:00:00 CST 1997
- NANOGEN INC
A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic formats. These reactions include nucleic acid hybridization,...
US6673637 (B2), filed
Thu Sep 20 00:00:00 CDT 2001
, published
Tue Jan 06 00:00:00 CST 2004
- KLA TENCOR TECHNOLOGIES
Methods and systems for monitoring semiconductor fabrication processes are provided. A system may include a stage configured to support a specimen and coupled to a measurement device. The measurement device may include an illumination system and a detection...
US6919186 (B2), filed
Fri Sep 28 00:00:00 CDT 2001
, published
Tue Jul 19 00:00:00 CDT 2005
- AMERSHAM PLC
The present invention provides novel engineered derivatives of green fluorescent protein (GFP) which have an amino acid sequence which is modified by amino acid substitution compared with the amino acid sequence of wild type Green Fluorescent Protein. The...
US6633831 (B2), filed
Thu Sep 20 00:00:00 CDT 2001
, published
Tue Oct 14 00:00:00 CDT 2003
- KLA TENCOR TECHNOLOGIES
Methods and systems for monitoring semiconductor fabrication processes are provided. A system may include a stage configured to support a specimen and coupled to a measurement device. The measurement device may include an illumination system and a detection...
US4376110 (A), filed
Mon Aug 04 00:00:00 CDT 1980
, published
Tue Mar 08 00:00:00 CST 1983
- HYBRITECH INC
"Two-site" or "sandwich" immunometric assay techniques for determination of the presence and/or concentration of antigenic substances in fluids using monoclonal antibodies. One monoclonal antibody is presented in a soluble labeled form and a second monoclonal...
US5571401 (A), filed
Mon Mar 27 00:00:00 CST 1995
, published
Tue Nov 05 00:00:00 CST 1996
- CALIFORNIA INST OF TECHN
Chemical sensors for detecting analytes in fluids comprise first and second conductive elements (e.g. electrical leads) electrically coupled to and separated by a chemically sensitive resistor which provides an electrical path between the conductive elements....
US6134003 (A), filed
Tue Feb 27 00:00:00 CST 1996
, published
Tue Oct 17 00:00:00 CDT 2000
- MASSACHUSETTS INST TECHNOLOGY
An imaging system for performing optical coherence tomography includes an optical radiation source; a reference optical reflector; a first optical path leading to the reference optical reflector; and a second optical path coupled to an endoscopic unit. The...
US6484566 (B1), filed
Mon Nov 27 00:00:00 CST 2000
, published
Tue Nov 26 00:00:00 CST 2002
- RHEOLOGICS INC
A scanning rheometer is presented for the rheological property measurement of electrorheological (ER) and magnetorheological (MR) fluids using a non-linear viscoplastic model, based on the fluid height variation with respect to time. The rheometer basically...
US7150994 (B2), filed
Wed Mar 07 00:00:00 CST 2001
, published
Tue Dec 19 00:00:00 CST 2006
- SYMYX TECHNOLOGIES INC
Parallel flow reaction systems comprising four or more reaction channels are disclosed. Distribution systems, and parallel flow reaction systems comprising such distribution systems are also disclosed. Specifically, the distribution systems comprise one or...
US4404065 (A), filed
Mon Jan 14 00:00:00 CST 1980
, published
Tue Sep 13 00:00:00 CDT 1983
- ENVIROMENTAL SCIENCES ASSOCIAT
An electrochemical detection apparatus is provided. The apparatus comprises a flow-cell having at least one active testing electrode, at least one reference electrode, and at least one counter electrode. Each electrode comprises a liquid impervious solid body...
US7326539 (B2), filed
Mon Sep 22 00:00:00 CDT 2003
, published
Tue Feb 05 00:00:00 CST 2008
- MAX PLANCK GESELLSCHAFT
The present invention relates to a method and a device for screening with cells immobilized on electrodes by using a low-salt medium. In particular, a method is disclosed for determining whether a substance is a modulator of a target component in a cell...
US7192734 (B2), filed
Wed Nov 27 00:00:00 CST 2002
, published
Tue Mar 20 00:00:00 CDT 2007
- MILLIPORE CORP
The invention relates to a method of testing for the presence of microorganisms in a gaseous environment comprising hydrogen peroxide, comprising the following steps: (i) bringing the gaseous environment comprising the hydrogen peroxide into contact with an...
US5750657 (A), filed
Mon Oct 18 00:00:00 CDT 1993
, published
Tue May 12 00:00:00 CDT 1998
- SQUIBB BRISTOL MYERS CO
The subject invention relates to methods and compositions using nondynamic fibrin monomer which is selectively converted to a fibrin polymer which serves as the fibrin sealant.
US6816249 (B2), filed
Tue Jul 17 00:00:00 CDT 2001
, published
Tue Nov 09 00:00:00 CST 2004
- KLA TENCOR CORP
The broadband brightfield/darkfield wafer inspection system provided receives broadband brightfield illumination information via a defect detector, which signals for initiation of darkfield illumination. The defect detector forms a two dimensional histogram of...
US7101969 (B1), filed
Thu Oct 12 00:00:00 CDT 2000
, published
Tue Sep 05 00:00:00 CDT 2006
- TARGANTA THERAPEUTICS
This invention relates to newly identified polynucleotides and polypeptides, and their production and uses, as well as their variants, agonists and antagonists, and their uses. In particular, the invention relates to polynucleotides and polypeptides of a...
US4567043 (A), filed
Wed Jun 15 00:00:00 CDT 1983
, published
Tue Jan 28 00:00:00 CST 1986
- AMERICAN HOME PROD
An efficacious parenterally administered modified live Canine Corona virus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent Canine Corona virus is produced. A method for...
US7371563 (B2), filed
Mon Jul 29 00:00:00 CDT 2002
, published
Tue May 13 00:00:00 CDT 2008
- SURFACE LOGIX INC
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on...
US5268852 (A), filed
Fri Oct 25 00:00:00 CDT 1991
, published
Tue Dec 07 00:00:00 CST 1993
- ROSEMOUNT ANALYTICAL INC
An apparatus and method for measuring potentiometric electrode impedance for diagnostic purpose while continuously reading the results of the process value. A square wave is applied to an external circuit, which in turn is coupled to an electrode assembly...
US6692437 (B2), filed
Tue Aug 28 00:00:00 CDT 2001
, published
Tue Feb 17 00:00:00 CST 2004
- RHEOLOGICS INC
A method for obtaining the viscosity of the circulating blood of a living being using an adulterated blood sample and a correlation factor obtained from a circulating blood viscometer.
US7198906 (B2), filed
Thu Jan 02 00:00:00 CST 2003
, published
Tue Apr 03 00:00:00 CDT 2007
- DAIKIN IND LTD
Disclosed herein is a method for determining the drug sensitivity of a microbe which comprises pouring a microbial suspension into each of the compartments or wells at a position which is in the vicinity of an electrode for measuring dissolved oxygen...
US4859609 (A), filed
Wed Apr 30 00:00:00 CDT 1986
, published
Tue Aug 22 00:00:00 CDT 1989
- GENENTECH INC
US5519212 (A), filed
Tue Jan 31 00:00:00 CST 1995
, published
Tue May 21 00:00:00 CDT 1996
- DIGITAL INSTR INC
An atomic force microscope in which a probe tip is oscillated at a resonant frequency and at amplitude setpoint and scanned across the surface of a sample, which may include an adsorbed water layer on its surface, at constant amplitude in intermittent contact...
US7294154 (B2), filed
Tue Oct 25 00:00:00 CDT 2005
, published
Tue Nov 13 00:00:00 CST 2007
- HISAMITSU PHARMACEUTICAL CO
A microorganism staining agent characterized in that an alkali substance and a diazo dye or xanthene dye are contained therein; and a method of detecting microorganisms with the use of the agent. There are provided a microorganism staining agent which resolves...
US6891627 (B1), filed
Thu Sep 20 00:00:00 CDT 2001
, published
Tue May 10 00:00:00 CDT 2005
- KLA TENCOR TECH CORP
Methods and systems for monitoring semiconductor fabrication processes are provided. A system may include a stage configured to support a specimen and coupled to a measurement device. The measurement device may include an illumination system and a detection...
US4970053 (A), filed
Fri Aug 18 00:00:00 CDT 1989
, published
Tue Nov 13 00:00:00 CST 1990
- BECKMAN INSTRUMENTS INC
A reagent cartridge for use in an automated clinical analyzer, the reagent cartridge including a plurality of storage compartments each including wall members. The reagent cartridge includes connecting members formed integrally with the storage compartments...
US7241571 (B2), filed
Fri Dec 19 00:00:00 CST 2003
, published
Tue Jul 10 00:00:00 CDT 2007
- UNIV CALIFORNIA
5-LO is expressed in the monocyte/macrophages (mono/mac) and foam cells of atherosclerotic lesions and is differentially expressed in CAST and CON6 mice relative to B6 mice. Mice heterozygous for a null mutation of 5-LO, when placed on an LDLR-/- background,...
US6090573 (A), filed
Wed Mar 03 00:00:00 CST 1999
, published
Tue Jul 18 00:00:00 CDT 2000
A method is presented for detecting eubacteria and fungus in biological samples, and, if present, determining their antibiotic sensitivity, where the presence and amount of eubacteria or fungus is measured by means of catalytically inactive murein binding...
US5769540 (A), filed
Wed Jan 12 00:00:00 CST 1994
, published
Tue Jun 23 00:00:00 CDT 1998
- LUXTRON CORP
Thermal, optical, physical and chemical characteristics of a substrate (11) surface are determined with non-contact optical techniques that include illuminating (23) the surface with radiation having a ripple intensity characteristic (51), and then measuring...
US4299916 (A), filed
Wed Dec 26 00:00:00 CST 1979
, published
Tue Nov 10 00:00:00 CST 1981
- SYVA CO
An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) of immunogens-ligand and receptor. The method has two basic elements: a solid surface to which one of...
US6168956 (B1), filed
Wed May 29 00:00:00 CDT 1991
, published
Tue Jan 02 00:00:00 CST 2001
- BECKMAN COULTER INC
An assay device for the performance of immunochromatographic assays and other assays has two principal parts, a first opposable component and a second opposable component. The first opposable component can contain a sample preparation means and a second...
US4271145 (A), filed
Mon Oct 22 00:00:00 CDT 1979
, published
Tue Jun 02 00:00:00 CDT 1981
- MASSACHUSETTS GEN HOSPITAL
Cell lines for producing monoclonal antibodies to hepatitis virus are established by immunizing animal lymphocytes with hepatitis antigen to form antibody producing cells which then are fused with myeloma cells. The resultant somatic cell hybrids can be...
US5382659 (A), filed
Tue Jun 07 00:00:00 CDT 1994
, published
Tue Jan 17 00:00:00 CST 1995
- CIBA GEIGY CORP
The invention relates to novel aromatic acids, especially to compounds of formula IMAGE (I) wherein R1 is lower alkyl, R2 is lower alkyl, R3 is hydrogen, carboxy or sulfo, R4 is carboxy or sulfo, G is an unsubstituted or substituted 1,4-phenylene group or...
US7063829 (B2), filed
Wed Nov 06 00:00:00 CST 2002
, published
Tue Jun 20 00:00:00 CDT 2006
- INSTITU CURIE
The invention concerns peptide fragments of the WASP family proteins, or peptides derived from said fragments, and their uses in particular for preparing reagents for use in implementing a method for detecting or screening molecules with inhibiting or...
US6916648 (B2), filed
Wed Oct 24 00:00:00 CDT 2001
, published
Tue Jul 12 00:00:00 CDT 2005
- GENENTECH INC
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptid...
US7291329 (B2), filed
Mon Apr 15 00:00:00 CDT 2002
, published
Tue Nov 06 00:00:00 CST 2007
- GENENTECH INC
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptid...
US5153519 (A), filed
Thu Feb 28 00:00:00 CST 1991
, published
Tue Oct 06 00:00:00 CDT 1992
- WENTWORTH WAYNE E
A spark detection apparatus is set forth and incorporates a closed chamber for receiving a carrier gas flowing therethrough between inlets and outlets, and the carrier gas is exposed to a pair of electrodes forming a spark across the chamber and through the...
US4888281 (A), filed
Tue Nov 27 00:00:00 CST 1984
, published
Tue Dec 19 00:00:00 CST 1989
- IGEN INC
A method for increasing the rate of chemical reactions involving the conversion of at least one reactant to at least one product involves contacting the reactant with an appropriate monoclonal antibody under conditions permitting the formation of a complex...
US5784162 (A), filed
Tue Dec 12 00:00:00 CST 1995
, published
Tue Jul 21 00:00:00 CDT 1998
- APPLIED SPECTRAL IMAGING LTD
According to the present invention there are provided spectral imaging methods for biological research, medical diagnostics and therapy comprising the steps of (a) preparing a sample to be spectrally imaged; (b) viewing the sample through an optical device,...
US5571410 (A), filed
Wed Jun 07 00:00:00 CDT 1995
, published
Tue Nov 05 00:00:00 CST 1996
- HEWLETT PACKARD CO
A miniaturized total analysis system (" mu -TAS") comprising a miniaturized planar column device is described for use in liquid phase analysis. The mu -TAS comprises microstructures fabricated by laser ablation in a variety of novel support substrates. The ...
US6267946 (B1), filed
Wed Feb 24 00:00:00 CST 1999
, published
Tue Jul 31 00:00:00 CDT 2001
A method of reducing the percentage of Epstein-Barr virus genome-carrying cells which exhibit Epstein-Barr virus early antigen induction, wherein the Epstein-Barr virus genome-carrying cells have been cultivated in the presence of a tumor-promoting chemical...
US4383031 (A), filed
Thu Jun 21 00:00:00 CDT 1979
, published
Tue May 10 00:00:00 CDT 1983
- MILES LAB
A homogeneous specific binding assay which employs a substance having reactant activity, i.e., a reactant, in a chemiluminescent reaction as a labeling substance in the detection of a ligand in a liquid medium. The assay employs a conjugate formed of a...
US6497872 (B1), filed
Wed Jun 07 00:00:00 CDT 1995
, published
Tue Dec 24 00:00:00 CST 2002
- NEUROSPHERES HOLDINGS LTD
The invention provides methods of transplanting multipotent neural stem cell progeny to a host by obtaining a population of cells derived from mammalian neural tissue containing at least one multipotent CNS multipotent neural stem cell; culturing the neural...
US5741462 (A), filed
Tue Apr 25 00:00:00 CDT 1995
, published
Tue Apr 21 00:00:00 CDT 1998
- IRORI
Combinations, called matrices with memories, of matrix materials with remotely addressable or remotely programmable recording devices that contain at least one data storage unit are provided. The matrix materials are those that are used in as supports in solid...
US4981784 (A), filed
Wed Nov 30 00:00:00 CST 1988
, published
Tue Jan 01 00:00:00 CST 1991
- SALK INST FOR BIOLOGICAL STUDI
US6804004 (B1), filed
Tue May 30 00:00:00 CDT 2000
, published
Tue Oct 12 00:00:00 CDT 2004
- J A WOOLLAM CO INC
Disclosed are multi-element lenses which demonstrate reduced achromatic focal length and reduced electromagentic beam spot size dispersal effects in ellipsometer and polarimeter systems. Also disclosed is methodology for evaluating parameters in parameterized...
US4577153 (A), filed
Mon May 06 00:00:00 CDT 1985
, published
Tue Mar 18 00:00:00 CST 1986
- STOLAR INC
Instrumentation and procedures for detecting geological anomalies occurring in layered coal formations. The instrumentation comprises a medium frequency continuous wave narrowband FM transmitter and receiver pair. Two instrument configurations are disclosed...
US7160423 (B2), filed
Tue Mar 04 00:00:00 CST 2003
, published
Tue Jan 09 00:00:00 CST 2007
- CALIPER LIFE SCIENCES INC
Methods and systems that employ hybrid fluid flow profiles for optimized movement of materials through channel networks. These systems employ hybrid pressure-based and electrokinetic based flow systems for moving materials through interconnected channel...
US6956644 (B2), filed
Tue Jun 26 00:00:00 CDT 2001
, published
Tue Oct 18 00:00:00 CDT 2005
- KLA TENCOR TECH CORP
A method for detecting an anomaly on a top surface of a substrate comprises directing a first radiation beam having a first wavelength at the top surface of the substrate at a first angle measured from normal, and directing a second radiation beam having a...
US4471305 (A), filed
Tue Dec 15 00:00:00 CST 1981
, published
Tue Sep 11 00:00:00 CDT 1984
- UNIV CALIF
An imaging NMR scanner obtains plural spin echo signals during each of successive measurement cycles permitting determination of the T2 parameter for each display pixel after but a single measurement sequence. The amplitude of the NMR spin echo responses is...
US4700561 (A), filed
Mon Feb 24 00:00:00 CST 1986
, published
Tue Oct 20 00:00:00 CDT 1987
- DOUGHERTY STEVEN J
A method and apparatus for determining entrained gas-phase content of process streams comprising collection, isolation, and compression of a process sample, measurement of the compressive behavior, and calculation of the volume of entrained gas-phase by means...
US6427731 (B1), filed
Mon Dec 13 00:00:00 CST 1999
, published
Tue Aug 06 00:00:00 CDT 2002
- AMERSHAM PHARM BIOTECH AB
This invention is directed to a cassette chemical immobilization and treatment system and method for enabling the performance of various complex chemistries with minimal human intervention, near-zero dead volume, and flow-through protocols pursuant to a...
US7166459 (B2), filed
Fri Mar 15 00:00:00 CST 2002
, published
Tue Jan 23 00:00:00 CST 2007
- SURFACE LOGIX INC
The present invention discloses a test device including a support member; a top member mounted to the support member, wherein in the support member and the top member are configured such that they together define a discrete chamber. The discrete chamber...
US5910580 (A), filed
Mon Dec 08 00:00:00 CST 1997
, published
Tue Jun 08 00:00:00 CDT 1999
- LILLY CO ELI
The invention provides isolated nucleic acid compounds encoding HI1648 of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said...
US6312697 (B1), filed
Wed Feb 24 00:00:00 CST 1999
, published
Tue Nov 06 00:00:00 CST 2001
A method of reducing the percentage of Epstein-Barr virus genome-carrying cells which exhibit Epstein-Barr virus early antigen induction, where the Epstein-Barr virus genone-carrying cells have been cultivated in the presence of at least one tumor-promoting...
US7101661 (B1), filed
Tue Jun 20 00:00:00 CDT 2000
, published
Tue Sep 05 00:00:00 CDT 2006
- NANOGEN INC
A system for performing molecular biological diagnosis, analysis and multistep and multiplex reactions utilizes a selfaddressable, selfassembling microelectronic system for actively carrying out controlled reactions in microscopic formats. Preferably, a...
US4854710 (A), filed
Thu Jul 23 00:00:00 CDT 1987
, published
Tue Aug 08 00:00:00 CDT 1989
- THERMA WAVE INC
A method and apparatus are disclosed for evaluating surface and subsurface features in a semiconductor sample. In operation, a periodic energy source is applied to the surface of the semiconductor sample to generate a periodic electron-hole plasma. This plasma...
US6284224 (B1), filed
Wed Feb 24 00:00:00 CST 1999
, published
Tue Sep 04 00:00:00 CDT 2001
A method of treating a group of mammals which have been topically exposed to a tumor promoter or a tumor initiator so as to reduce the percentage of mammals which exhibit formation of epidermal tumors. The topically exposed tissue is treated with an acetone...
US4978614 (A), filed
Thu Jul 20 00:00:00 CDT 1989
, published
Tue Dec 18 00:00:00 CST 1990
- TROPIX INC
In an assay method in which a member of a specific binding pair is detected by means of an optically detectable reaction, the improvement wherein the optically detectable reaction includes the reaction, with an enzyme, of a dioxetane having the formula IMAGE...
US4375414 (A), filed
Fri Jan 21 00:00:00 CST 1977
, published
Tue Mar 01 00:00:00 CST 1983
- STRAHILEVITZ MEIR
Immunoassays of psychoactive drugs including psychotomimetic drugs, narcotic drugs, and tetrahydrocannabinols and treatment methods based on the antigenic properties of protein conjugates of these drugs. These methods are based upon treating the psychoactive...
US6448091 (B1), filed
Mon Nov 07 00:00:00 CST 1994
, published
Tue Sep 10 00:00:00 CDT 2002
- IGEN INT INC
Methods and apparatus for performing a binding assay for an analyte of interest present in a sample are described. The methods include the steps of: forming a composition containing the sample, an assay-performance-substance which contains a component linked...
US6732573 (B2), filed
Mon Apr 22 00:00:00 CDT 2002
, published
Tue May 11 00:00:00 CDT 2004
- RHEOLOGICS INC
An apparatus and method for determining the viscosity of the circulating blood of a living being over plural shear rates caused by a decreasing pressure differential by monitoring the changing weight of the blood, or the changing level of a column of blood...
US5814469 (A), filed
Wed Jun 07 00:00:00 CDT 1995
, published
Tue Sep 29 00:00:00 CDT 1998
- CHIRON CORP
Methods are disclosed for diagnosing diseases resulting from undesirable cell adhesion of IL-1 receptor positive cells to biological materials, particular to endothelial cells, or autoimmune related diseases, preferably graft versus host disease, or IL-1...
US5824549 (A), filed
Fri Jun 02 00:00:00 CDT 1995
, published
Tue Oct 20 00:00:00 CDT 1998
- CHIRON CORP
Medicaments and methods of using the same are disclosed for treating or preventing diseases resulting from undesirable cell adhesion of IL-1 receptor positive cells to biological materials, particular to endothelial cells, or autoimmune related diseases,...
US6051226 (A), filed
Thu Dec 30 00:00:00 CST 1993
, published
Tue Apr 18 00:00:00 CDT 2000
- INST OF VIROLOGY SLOVAK ACADEM
A new gene-MN-and proteins/polypeptides encoded therefrom are disclosed. Recombinant nucleic acid molecules for expressing MN proteins/polypeptides and fusion proteins are provided. Expression of the MN gene is disclosed as being associated with tumorigenicity...
US5985356 (A), filed
Tue Oct 18 00:00:00 CDT 1994
, published
Tue Nov 16 00:00:00 CST 1999
- SYMYX TECHNOLOGIES INC
Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to...
US6429186 (B1), filed
Mon Sep 19 00:00:00 CDT 1994
, published
Tue Aug 06 00:00:00 CDT 2002
- GENENTECH INC
We have discovered that growth hormones form ternary complexes with their receptors in which site 1 on the hormone first binds to one molecule of receptor and then hormone site 2 then binds to another molecule of receptor, thereby producing a 1:2 complex. We...
US7338168 (B2), filed
Thu Jan 15 00:00:00 CST 2004
, published
Tue Mar 04 00:00:00 CST 2008
- ANGKOR TECHNOLOGY LLP
An imaging system, methodology, and various applications are provided to facilitate optical imaging performance. The system contains a sensor having one or more receptors and an image transfer medium to scale the sensor and receptors in accordance with...
US4632901 (A), filed
Fri May 11 00:00:00 CDT 1984
, published
Tue Dec 30 00:00:00 CST 1986
- HYBRITECH INC
Disclosed herein is an apparatus and process for conducting immunoassays. The apparatus comprises a first member which is a membrane or a filter to which is bound an antibody, typically a monoclonal antibody, or which is capable of extracting cells from a...
US4767206 (A), filed
Mon Dec 24 00:00:00 CST 1984
, published
Tue Aug 30 00:00:00 CDT 1988
- FLOW CYTOMETRY STANDARDS CORP
A method of calibrating a flow cytometer is based on a set of highly uniform microbeads associated with a fluorescent dye in such a way that the microbeads have the same excitation and emission spectral properties as the samples which are to be measured. The...
US6452371 (B1), filed
Tue May 02 00:00:00 CDT 2000
, published
Tue Sep 17 00:00:00 CDT 2002
- GAMBRO INC
A flow rate of a fluid flowing in a tube is quantitatively determined by altering the electrical conductivity of the fluid by injection of a bolus of saline. The electrical conductivity of the altered conductivity is measured over the time it takes the altered...
US7177020 (B2), filed
Fri May 13 00:00:00 CDT 2005
, published
Tue Feb 13 00:00:00 CST 2007
- RENESAS TECH CORP
An apparatus and method for detecting defects on a specimen includes an illumination optical unit which obliquely projects a laser onto a region which is longer in one direction on a surface of a specimen than in a transverse direction, a table unit which...
US4422942 (A), filed
Wed Sep 09 00:00:00 CDT 1981
, published
Tue Dec 27 00:00:00 CST 1983
- ISCO INC
To stabilize flow rate in a single-stroke, syringe-type high pressure pump to a constant value after turn-on, a control system increases the pump speed until equilibrium conditions are reached and then pumps at the preset rate. In one embodiment, the control...
US5097492 (A), filed
Mon Feb 12 00:00:00 CST 1990
, published
Tue Mar 17 00:00:00 CST 1992
- FOUR PI SYSTEMS CORP
A tomographic inspection system wherein the electron beam of a microfocus X-ray tube is deflected in a circular scan pattern onto the tube anode in synchronization with a rotating detector that converts the X-ray shadowgraph into an optical image and derotates...
US5679321 (A), filed
Tue Jun 06 00:00:00 CDT 1995
, published
Tue Oct 21 00:00:00 CDT 1997
- GLYCOMED INC
Compounds that are synthetically inexpensive to make relative to the naturally occurring selectin ligands and that retain selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs or...
US5677195 (A), filed
Fri Nov 20 00:00:00 CST 1992
, published
Tue Oct 14 00:00:00 CDT 1997
- AFFYMAX TECH NV
A method and device for forming large arrays of polymers on a substrate (401). According to a preferred aspect of the invention, the substrate is contacted by a channel block (407) having channels (409) therein. Selected reagents are delivered through the...
US7223236 (B2), filed
Fri Sep 09 00:00:00 CDT 2005
, published
Tue May 29 00:00:00 CDT 2007
- HEALTH HERO NETWORK INC
Monitoring airflow from a person is accomplished by using a central server arranged to receive and communicate data together with at least one microprocessor-based subsystem. The subsystem includes a microprocessor, a display and a memory. It presents...
US6184027 (B1), filed
Thu Mar 04 00:00:00 CST 1999
, published
Tue Feb 06 00:00:00 CST 2001
- SUPERVISORS LOUISIANA STATE UN
Catalytically inactive murein binding enzyme diagnostic reagents and methods and kits for detecting eubacteria and fungus in biological samples.
US7081353 (B2), filed
Thu Jan 02 00:00:00 CST 2003
, published
Tue Jul 25 00:00:00 CDT 2006
- DAIKIN IND LTD
A method and apparatus wherein measurement current values output from a first oxygen sensor and a second oxygen sensor are time sequentially measured. Each moving average value is calculated from each sequential measurement current value. Each time differentia...
