Top 100 US Patents in Acyclic/Carbocyclic Compounds
section c - chemistry; metallurgy > organic chemistry > acyclic or carbocyclic compounds
Sorted by IPQ® Score, an objective measure of patent quality. View scores and methodology at PatentRatings.com. You can also view all by publication date instead.
US6956131 (B2), filed
Fri Apr 13 00:00:00 CDT 2001
, published
Tue Oct 18 00:00:00 CDT 2005
- PHARMACIA CORP
The present invention is directed to a compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: RSUB2 /SUBis selected from the group consisting of H and methyl; and RSUB2 /SUBis selected from the group consisting of H and methyl. The...
US6702705 (B1), filed
Wed Feb 22 00:00:00 CST 1995
, published
Tue Mar 09 00:00:00 CST 2004
- IGEN INT INC
Catalytic antibodies are disclosed. The catalytic antibodies are specific for prodrug compounds. The catalytic antibodies enhance cleavage of an active drug moiety from a prodrug residue, thereby activating the drug.
US5811578 (A), filed
Wed Aug 20 00:00:00 CDT 1997
, published
Tue Sep 22 00:00:00 CDT 1998
- MONSANTO CO
Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acards that prey on agricultural crops. Polar compounds are particularly useful for systemic control of pests.
US5246692 (A), filed
Thu Aug 22 00:00:00 CDT 1991
, published
Tue Sep 21 00:00:00 CDT 1993
- US HEALTH
New polysubstituted diethylenetriaminepentaacetic acid chelates and protein conjugates of the same are described together with the methods of preparing such compounds. A method of delivering radiolabelled compound of the present invention to a target site...
US4700009 (A), filed
Tue Jan 28 00:00:00 CST 1986
, published
Tue Oct 13 00:00:00 CDT 1987
- HOFFMANN LA ROCHE
The present disclosure is concerned with a novel process for the manufacture of substituted benzaldehydes, namely of benzaldehydes of the formula IMAGE I wherein R represents a methoxy or tert.butyl group. The compounds of formula I are known substances,...
US4450289 (A), filed
Fri May 21 00:00:00 CDT 1982
, published
Tue May 22 00:00:00 CDT 1984
- SHELL OIL CO
A process for producing butenyl acetate which comprises reacting butadiene and acetic acid in the presence of a catalyst comprising a sulfonic acid ion exchange resin modified with a quaternary phosphonium salt.
US5700840 (A), filed
Tue May 23 00:00:00 CDT 1995
, published
Tue Dec 23 00:00:00 CST 1997
- MONSANTO CO
Fluorinated alkene compounds useful for controlling nematodes, insects, and acarids that prey on agricultural crops, these compounds having the formula BrCF2CFClCH2CO-R where R is R1 or R2. R1 is -SR5, halogen, -NHOH or -NR5R6, where R5 and R6 are independentl...
US6803484 (B2), filed
Wed Dec 24 00:00:00 CST 2003
, published
Tue Oct 12 00:00:00 CDT 2004
- LILLY CO ELI
The present invention relates to a compound of formula (Ia) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders.
US7420088 (B2), filed
Mon Aug 22 00:00:00 CDT 2005
, published
Tue Sep 02 00:00:00 CDT 2008
- BASF AG
The present invention relates to a process for preparing formic acid by thermally decomposing ammonium formates of tertiary amines A, wherein the tertiary amine A on which the ammonium formate is based has a boiling point at atmospheric pressure in the range...
US4869887 (A), filed
Fri Oct 30 00:00:00 CST 1987
, published
Tue Sep 26 00:00:00 CDT 1989
- DIJK CHRISTIAAN P VAN
An integrated ammonia urea process where the reaction of carbon dioxide and ammonia is in a urea reactor having a condensing section, a reaction section having more than one stage and a stripping section. The raw ammonia synthesis gas containing carbon dioxide...
US5003080 (A), filed
Wed Feb 01 00:00:00 CST 1989
, published
Tue Mar 26 00:00:00 CST 1991
- WARNER LAMBERT CO
US4401583 (A), filed
Thu Jun 24 00:00:00 CDT 1982
, published
Tue Aug 30 00:00:00 CDT 1983
- INT FLAVORS FRAGRANCES INC
Described in the compound, 4-methyl-3-cyclohexene-1-carboxylic acid having the structure: IMAGE and the use thereof in augmenting or enhancing the aroma of perfume compositions, perfumed articles (e.g., solid or liquid anionic, cationic, nonionic or...
US7476740 (B2), filed
Thu Mar 27 00:00:00 CST 2003
, published
Tue Jan 13 00:00:00 CST 2009
- ORGANIX INC
The present invention provides novel tropane compounds and methods for their use.
US4271313 (A), filed
Fri Oct 26 00:00:00 CDT 1979
, published
Tue Jun 02 00:00:00 CDT 1981
- UPJOHN CO
The present invention provides novel 19-hydroxy-cis-4,5-didehydro-13,14-dihydro-PG1 Analogs methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
US4426222 (A), filed
Mon Jan 04 00:00:00 CST 1982
, published
Tue Jan 17 00:00:00 CST 1984
- SCHERING AG
Novel carbaminic acid phenyl esters of the general formula IMAGE are described, in which R1 is C1-C2-alkoxy-C1-C2-alkyl, di-C1-C2-alkoxy-C1-C2-alkyl, cyano-C1-C2-alkyl, halogen-C1-C2-alkyl, phenyl-C1-C2-alkyl, 1,3-dioxolan-2-yl-methyl, 2-methyl-1,3-dioxolan-...
US5059288 (A), filed
Tue Nov 21 00:00:00 CST 1989
, published
Tue Oct 22 00:00:00 CDT 1991
- HARBORCHEM
High purity isopropyl acetate and ethanol are recovered from a process stream containing isopropyl acetate, ethanol and water by a multiple step process including extracting substantially all of the ethanol from the stream using water as a solvent, stripping...
US5968916 (A), filed
Mon Jan 12 00:00:00 CST 1998
, published
Tue Oct 19 00:00:00 CDT 1999
- MONSANTO CO
Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops. Polar compounds are particularly useful for systemic control of pests.
US4283558 (A), filed
Fri Oct 26 00:00:00 CDT 1979
, published
Tue Aug 11 00:00:00 CDT 1981
- UPJOHN CO
The present invention provides novel 2-decarboxy-2-hydroxymethyl-19,20-didehydro-13,14-dihydro-PG1 compounds methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
US6989135 (B2), filed
Fri Jun 08 00:00:00 CDT 2001
, published
Tue Jan 24 00:00:00 CST 2006
- SYNTROLEUM CORP
A Fischer-Tropsch-based hydrocarbon conversion process involves compressing air in a compressor section of a gas turbine, delivering a portion of the compressed air to a combustor of the gas turbine, delivering a portion of the compressed air to a Fischer-Trop...
US6222079 (B1), filed
Thu Oct 28 00:00:00 CDT 1999
, published
Tue Apr 24 00:00:00 CDT 2001
- OCCIDENTAL CHEM CO
Disclosed is a method of increasing the percentage of certain isomers made when di or tri-substituted benzenes are chlorinated in the presence of a Friedel-Crafts catalyst. The use of about 0.001 to about 1 wt % a cocatalyst during chlorination alters the...
US5922908 (A), filed
Thu Mar 27 00:00:00 CST 1997
, published
Tue Jul 13 00:00:00 CDT 1999
- TWENTY FIRST CENTURY RES CORP
This invention relates to methods of preparing dibasic acids, such as adipic acid for example, by oxidizing a hydrocarbon with a gas containing an oxidant, preferably oxygen. A respective hydrocarbon is reacted with a gaseous oxidant to form dibasic acid in a...
US6388094 (B1), filed
Mon Nov 01 00:00:00 CST 1999
, published
Tue May 14 00:00:00 CDT 2002
- SEARLE CO
A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde.
US4335022 (A), filed
Mon Dec 22 00:00:00 CST 1980
, published
Tue Jun 15 00:00:00 CDT 1982
- SHELL OIL CO
A novel siliceous composition prepared by impregnating porous silica with aluminum hydride and subsequently heating the impregnated silica to a temperature of from about 300 DEG C. to about 900 DEG C. in a non-oxidizing environment. The composition is useful...
US6716844 (B2), filed
Mon Dec 03 00:00:00 CST 2001
, published
Tue Apr 06 00:00:00 CDT 2004
- PHARMACIA CORP
An aromatic sulfonyl aipha-hydroxy hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed, as is a treatment process that comprises administering a contemplated aromatic sulfonyl alpha-hydroxy hydroxamic acid compound in...
US6828456 (B2), filed
Sat Sep 15 00:00:00 CDT 2001
, published
Tue Dec 07 00:00:00 CST 2004
- PHARMACIA CORP
The present invention relates to 2-amino-2-alkyl-3 hexenoic and hexynoic acid derivatives and their use in therapy, in particular their use as nitric oxide synthase inhibitors.
US7005450 (B2), filed
Wed Apr 07 00:00:00 CDT 2004
, published
Tue Feb 28 00:00:00 CST 2006
- PHARMACIA CORP
The present invention relates to 2-amino-2-alkyl-4 hexenoic and hexynoic acid derivatives and their use in therapy, in particular their use as nitric oxide synthase inhibitors.
US7459139 (B2), filed
Fri May 30 00:00:00 CDT 2003
, published
Tue Dec 02 00:00:00 CST 2008
- COUNCIL SCIENT IND RES
A cost-effective process is described for the preparation of a stable and non-hazardous brominating reagent containing 2:1 stoichiometric ratio of alkali bromide to alkali bromate. The process comprises of reacting alkaline bromine intermediate mixture,...
US4395366 (A), filed
Thu May 20 00:00:00 CDT 1982
, published
Tue Jul 26 00:00:00 CDT 1983
- INT FLAVORS FRAGRANCES INC
Described are compounds defined according to the generic structure: IMAGE wherein the dashed line represents a carbon-carbon single bond or a carbon-carbon double bond; and one of R1 and R2 is methyl and the other of R1 and R2 is hydrogen. In addition,...
US5382659 (A), filed
Tue Jun 07 00:00:00 CDT 1994
, published
Tue Jan 17 00:00:00 CST 1995
- CIBA GEIGY CORP
The invention relates to novel aromatic acids, especially to compounds of formula IMAGE (I) wherein R1 is lower alkyl, R2 is lower alkyl, R3 is hydrogen, carboxy or sulfo, R4 is carboxy or sulfo, G is an unsubstituted or substituted 1,4-phenylene group or...
US5952462 (A), filed
Wed Nov 02 00:00:00 CST 1994
, published
Tue Sep 14 00:00:00 CDT 1999
- IGEN INT INC
Antigens capable of eliciting antibodies which can catalyze chemical reactions, in particular, the cleavage or formation of a peptide linkage, comprising a hapten or a hapten and a suitable carrier molecule are disclosed. Haptens include, among others, silicon...
US5545674 (A), filed
Tue Jan 24 00:00:00 CST 1995
, published
Tue Aug 13 00:00:00 CDT 1996
- EXXON RESEARCH ENGINEERING CO
A supported particulate cobalt catalyst is formed by dispersing cobalt, alone or with a metal promoter, particularly rhenium, as a thin catalytically active film upon a particulate support, especially a silica or titania support. This catalyst can be used to...
US4421535 (A), filed
Mon May 03 00:00:00 CDT 1982
, published
Tue Dec 20 00:00:00 CST 1983
- EL PASO HYDROCARBONS
A sweet natural gas stream is stripped of water and hydrocarbon components heavier than methane to substantially any selected degree by countercurrent extraction with polyethylene glycol dimethyl ether while at pipeline pressures. The stripped natural gas...
US5986104 (A), filed
Thu Nov 12 00:00:00 CST 1998
, published
Tue Nov 16 00:00:00 CST 1999
- MONSANTO CO
Processes for preparing substituted 3-aryl-5-haloalkyl-pyrazoles and, specifically, for preparing C1-5 alkyl esters of 5-[1-(C1-5 alkyl)-4-halo-5-(C1-3 haloalkyl)-1H-pyrazole-3-yl]-2,4-dihalo-benzoic acids such as isopropyl 5-[4-bromo-1-methyl-5-(trifluorometh...
US6777583 (B2), filed
Mon Aug 26 00:00:00 CDT 2002
, published
Tue Aug 17 00:00:00 CDT 2004
- EXXONMOBIL OIL CORP
There is provided a substantially binder-free catalytic molecular sieve which has been modified by being ex situ selectivated with a silicon compound. The ex situ selectivation involves exposing the molecular sieve to at least two silicon impregnation...
US5055622 (A), filed
Wed Sep 12 00:00:00 CDT 1990
, published
Tue Oct 08 00:00:00 CDT 1991
- HOFFMANN LA ROCHE
US4411925 (A), filed
Wed Nov 05 00:00:00 CST 1980
, published
Tue Oct 25 00:00:00 CDT 1983
- PFIZER
Amides of L-aspartyl-D-amino acid dipeptides of the formula IMAGE (I) and physiologically acceptable cationic and acid addition salts thereof wherein Ra is methyl, ethyl, n-propyl or isopropyl; R is a branched member selected from the group consisting of...
US5364866 (A), filed
Fri Oct 30 00:00:00 CST 1992
, published
Tue Nov 15 00:00:00 CST 1994
- HOECHST ROUSSEL PHARMA
Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. The...
US5886034 (A), filed
Fri Mar 10 00:00:00 CST 1995
, published
Tue Mar 23 00:00:00 CST 1999
- R TECH UENO LTD
The novel 13,14-dihydro-15-keto prostaglandins E of the invention have remarkable preventive effects against ulcers. Further, the novel 13,14-dihydro-15-keto-prostaglandins E of the invention have an advatage that they have none of side effects which...
US4269775 (A), filed
Fri Aug 24 00:00:00 CDT 1979
, published
Tue May 26 00:00:00 CDT 1981
- CIBA GEIGY CORP
The invention relates to oximes of the formula IMAGE (I) wherein n is 0, 1 or 2 and m is 0 or 1, and wherein Ar is a phenyl radical IMAGE a naphthyl radical substituted by R2 and R3, a 5- to 10-membered heterocyclic radical which contains not more than...
US4332798 (A), filed
Wed Jan 30 00:00:00 CST 1980
, published
Tue Jun 01 00:00:00 CDT 1982
- FUJISAWA PHARMACEUTICAL CO
7-Substituted-3-cephem and cepham-4-carboxylic acids of formula (I) IMAGE (I) wherein R1 is amino or a protected amino, R2 is hydrogen, acyl, aryl which may be substituted with suitable substituent(s), lower alkyl substituted with suitable substituent(s),...
US4502921 (A), filed
Tue Aug 17 00:00:00 CDT 1982
, published
Tue Mar 05 00:00:00 CST 1985
- FOXBORO CO
Control of multiple distillation columns for producing anhydrous alcohol suitable for blending with gasoline to produce gasohol. The distillation process involves production of a first-stage distillate containing a predetermined amount of water, followed by...
US4576739 (A), filed
Mon Oct 01 00:00:00 CDT 1984
, published
Tue Mar 18 00:00:00 CST 1986
- INT FLAVORS FRAGRANCES INC
Described are tertiary hydroxyl carboxaldehydes defined according to the generic structure: IMAGE wherein the lines * * * * * and - - - - - - and/or + + + + + represent covalent carbon-carbon bonds when m does not=0; and wherein the lines + + + + + *...
US6316633 (B1), filed
Mon Oct 30 00:00:00 CST 2000
, published
Tue Nov 13 00:00:00 CST 2001
- HOFFMANN LA ROCHE
The present invention is concerned with a process for the manufacture of chiral succinic acid derivatives of formula (I)wherein R1 is (C1-C6) alkyl or benzyl, and the novel intermediates used therein.
US6656954 (B2), filed
Thu Nov 29 00:00:00 CST 2001
, published
Tue Dec 02 00:00:00 CST 2003
- PHARMACIA CORP
A sulfonyl divalent aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated sulfonyl divalent aromatic or heteroaromat...
US4346243 (A), filed
Thu Jul 16 00:00:00 CDT 1981
, published
Tue Aug 24 00:00:00 CDT 1982
- INT FLAVORS FRAGRANCES INC
Described are methyl substituted norbornane derivatives having the generic structure: IMAGE wherein R represents the nitrile moiety having the structure: -C 3BOND N] or the dimethoxymethyl moiety having the structure: IMAGE and wherein one of R1, or R2...
US5102934 (A), filed
Fri Mar 15 00:00:00 CST 1991
, published
Tue Apr 07 00:00:00 CDT 1992
- ETHYL CORP
Organic materials which are normallly susceptible to oxidative deterioration are stabilized with tertiary sulfonamide antioxidants corresponding to the formula: IMAGE wherein R and R' are independently selected from alkyl, aryl, and benzyl groups, R'' is...
US4608196 (A), filed
Fri Aug 23 00:00:00 CDT 1985
, published
Tue Aug 26 00:00:00 CDT 1986
- INT FLAVORS FRAGRANCES INC
Described are tertiary hydroxyl carboxaldehydes defined according to the generic structure: IMAGE wherein the lines * * * * * and - - - - - - and/or + + + + + represent covalent carbon-carbon bonds when m does not=0; and wherein the lines + + + + + *...
US4617144 (A), filed
Fri Aug 23 00:00:00 CDT 1985
, published
Tue Oct 14 00:00:00 CDT 1986
- INT FLAVORS FRAGRANCES INC
Described are tertiary hydroxyl carboxaldehydes defined according to the generic structure: IMAGE wherein the lines * * * * * and - - - - - - and/or + + + + + represent covalent carbon-carbon bonds when m does not=0; and wherein the lines + + + + + *...
US4554384 (A), filed
Mon Oct 01 00:00:00 CDT 1984
, published
Tue Nov 19 00:00:00 CST 1985
- INT FLAVORS FRAGRANCES INC
Described are tertiary hydroxyl carboxaldehydes defined according to the generic structure: IMAGE wherein the lines and - - - - - - and/or + + + + + represent covalent carbon-carbon bonds when m does not=0; and wherein the lines + + + + + and -...
US5648571 (A), filed
Wed Mar 27 00:00:00 CST 1996
, published
Tue Jul 15 00:00:00 CDT 1997
Methods for synthesis of chemical compounds by catalytic transfer hydrogenation comprise forming a mixture of a starting material, a hydrogen donor material and a catalyst. The catalyst is selected from a catalytic form of carbon, a polyethylene glycol phase...
US6620835 (B2), filed
Tue Jun 04 00:00:00 CDT 2002
, published
Tue Sep 16 00:00:00 CDT 2003
- WARNER LAMBERT CO
The present invention relates to a method of inhibiting matrix metalloproteinases using compounds that are dibenzofuran sulfonamide derivatives having the Formula IMore particularly, the present invention relates to a method of treating diseases in which...
US6113747 (A), filed
Wed Jun 30 00:00:00 CDT 1999
, published
Tue Sep 05 00:00:00 CDT 2000
- GRT INC
In a method of and apparatus for manufacturing methanol from methane a catalytic area is formed on the exterior of a hollow sintered stainless steel tube. Methane is maintained within the sintered stainless steel tube at predetermined pressure, and water...
US4584409 (A), filed
Fri Mar 08 00:00:00 CST 1985
, published
Tue Apr 22 00:00:00 CST 1986
- INT FLAVORS FRAGRANCES INC
Described are tertiary hydroxyl carboxaldehydes defined according to the generic structure: IMAGE wherein the lines * * * * * and - - - - - - and/or + + + + + represent covalent carbon-carbon bonds when m does not=0; and wherein the lines + + + + + *...
US6265440 (B1), filed
Wed May 06 00:00:00 CDT 1998
, published
Tue Jul 24 00:00:00 CDT 2001
- R TECH UENO LTD
The novel 13,14-dihydro-15-keto prostaglandins E of the invention have remarkable preventive effects against ulcers. Further, the novel 13,14-dihydro-15-keto-prostaglandins E of the invention have an advantage that they have none of side effects which...
US5281628 (A), filed
Fri Oct 04 00:00:00 CDT 1991
, published
Tue Jan 25 00:00:00 CST 1994
- AMERICAN CYANAMID CO
9-amino-7-(substituted amino)-6-demethyl-6-deoxytetracyclines having activity against a wide spectrum of organisms including organisms which are resistant to tetracyclines are disclosed. Also disclosed are intermediates and methods for making the novel...
US6312679 (B1), filed
Wed Mar 24 00:00:00 CST 1993
, published
Tue Nov 06 00:00:00 CST 2001
- DOW CHEMICAL CO
Starburst conjugates which are composed of at least one dendrimer in association with at least one unit of a carried agricultural, pharmaceutical, or other material have been prepared. These conjugates have particularly advantageous properties due to the...
US5618969 (A), filed
Thu Oct 19 00:00:00 CDT 1995
, published
Tue Apr 08 00:00:00 CDT 1997
- EISAI CO LTD
The present invention provides an industrially advantageous process for preparing a 2-alkyl-3-(biphenyl-4-yl)methyl-3H-imidazo[4,5-b]pyridine derivative represented by the following formula (II) which is a precursor of an antagonist against an angiotensin II...
US4465618 (A), filed
Wed Feb 24 00:00:00 CST 1982
, published
Tue Aug 14 00:00:00 CDT 1984
- FIRMENICH CIE
New spiranic compound, viz. 6-ethyl-2,10,10-trimethyl-1-oxaspiro[4.5]deca-3,6-diene, for use therefor as perfume or flavor-modifying ingredient.
US6153780 (A), filed
Thu Feb 24 00:00:00 CST 2000
, published
Tue Nov 28 00:00:00 CST 2000
- BAYER AG
Process for the preparation of octa-2,7-dienyl-1-amine by telomerization of butadiene with ammonia in a two-phase system in the presence of hydrophilic palladium complexes, characterized in that octa-2,7-dienyl-1-amine and octa-1,7-dienyl-3-amine are isolated...
US4235783 (A), filed
Fri Sep 07 00:00:00 CDT 1979
, published
Tue Nov 25 00:00:00 CST 1980
- UPJOHN CO
The present invention relates to novel trans-2,3,4,5-tetradehydro-9-deoxy-5,9a-epoxy-PGF1 amides, which are useful for inducing a variety of prostacyclin-like pharmacological effects. Accordingly, these compounds are useful pharmacological agents for the same...
US6787501 (B2), filed
Mon Jun 24 00:00:00 CDT 2002
, published
Tue Sep 07 00:00:00 CDT 2004
- EXXONMOBIL CHEM PATENTS INC
The invention relates to a molecular sieve catalyst composition, to a method of making or forming the molecular sieve catalyst composition, and to a conversion process using the catalyst composition. In particular, the invention is directed to making a...
US6121458 (A), filed
Thu Nov 12 00:00:00 CST 1998
, published
Tue Sep 19 00:00:00 CDT 2000
- MONSANTO CO
Processes for preparing substituted 3-aryl-5-haloalkyl-pyrazoles and, specifically, for preparing C1-5 alkyl esters of 5-[1-(C1-5 alkyl)-4-halo-5-(C1-3 haloalkyl)-1H-pyrazole-3-yl]-2,4-dihalo-benzoic acids such as isopropyl 5-[4-bromo-1-methyl-5-(trifluorometh...
US6429226 (B1), filed
Mon May 01 00:00:00 CDT 2000
, published
Tue Aug 06 00:00:00 CDT 2002
- PHARMACIA AB
The invention relates to ophthalmological compositions for topical treatment of glaucoma or ocular hypertension comprising an effective intraocular pressure reducing amount of a prostaglandin derivative of PGA, PGB, PGD, PGE or PGF, in which the omega chain...
US4259517 (A), filed
Fri Oct 26 00:00:00 CDT 1979
, published
Tue Mar 31 00:00:00 CST 1981
- UPJOHN CO
The present invention provides novel 19-hydroxy-trans-2,3-didehydro-13,14-dihydro-PG1 compounds methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
US7002036 (B2), filed
Thu May 15 00:00:00 CDT 2003
, published
Tue Feb 21 00:00:00 CST 2006
- GENZYME CORP
Non-natural amino acids such as 2-alkylated amino acids allow for the synthesis of a wider variety of peptidal and non-peptidal pharmaceutically active agents. A method of preparing a 2-alkyl amino acid involves a Michael-type addition of a nucleophile to a...
US6864357 (B2), filed
Fri Jul 19 00:00:00 CDT 2002
, published
Tue Mar 08 00:00:00 CST 2005
- AKZO NOBEL NV
The present invention relates to a process for the preparation of peptides using an excess of an activated carboxylic component to acylate an amino component, wherein after the acylation an amine comprising a free anion or a latent anion is used as a scavenger...
US5399244 (A), filed
Mon Dec 06 00:00:00 CST 1993
, published
Tue Mar 21 00:00:00 CST 1995
- GLITSCH
Benzene and other aromatics are separated from a stream of mixed hydrocarbons containing both aromatics and non-aromatics by extractive distillation with a solvent system containing dimethyl sulfoxide and optionally a co-solvent, preferably water, followed by...
US5973164 (A), filed
Thu Nov 12 00:00:00 CST 1998
, published
Tue Oct 26 00:00:00 CDT 1999
- MONSANTO CO
Processes for preparing substituted 3-aryl-5-haloalkyl-pyrazoles and, specifically, for preparing C1-5 alkyl esters of 5-[1-(C1-5 alkyl)-4-halo-5-(C1-3 haloalkyl)-1 H-pyrazole-3-yl]-2,4-dihalo-benzoic acids such as isopropyl 5-[4-bromo-1-methyl-5-(trifluoromet...
US6214176 (B1), filed
Fri Jan 07 00:00:00 CST 2000
, published
Tue Apr 10 00:00:00 CDT 2001
- GRT INC
In a method of and apparatus for manufacturing methanol and higher alcohols from natural gas a catalytic area is formed on the exterior of a gas permeable partition. Natural gas is maintained on the interior of the gas permeable partition at predetermined...
US5550204 (A), filed
Thu Jun 30 00:00:00 CDT 1994
, published
Tue Aug 27 00:00:00 CDT 1996
- BOEING CO
Crosslinkable, polyaromatic, polyether or polyester oligomers can have glass transition temperatures above 900 DEG F. while exhibiting desirable toughness for aerospace applications and ease of processing. A plurality (i.e. three or more) of generally linear...
US4549971 (A), filed
Thu May 24 00:00:00 CDT 1984
, published
Tue Oct 29 00:00:00 CST 1985
- INT FLAVORS FRAGRANCES INC
Described are methyl substituted pinyl oxopentenes and mixtures of same and uses thereof in augmenting or enhancing the aroma or taste of consumable materials including foodstuffs, chewing gums, toothpastes, medicinal products, chewing tobaccos, perfume...
US4631286 (A), filed
Thu Oct 25 00:00:00 CDT 1984
, published
Tue Dec 23 00:00:00 CST 1986
- HOECHST ROUSSEL PHARMA
There are disclosed compounds having the formula IMAGE wherein X is hydrogen, loweralkyl, loweralkoxy, halogen, hydroxy, nitro, NHCOR2 wherein R2 is loweralkyl, or a group of the formula NR3R4 wherein R3 and R4 are independently hydrogen or loweralkyl; R...
US4425341 (A), filed
Tue Mar 14 00:00:00 CST 1978
, published
Tue Jan 10 00:00:00 CST 1984
- FUJISAWA PHARMACEUTICAL CO
7-Substituted 3-cephem or cephem compounds characterized by the grouping, in the 7-position thereof, of the formula: R'-A-CONH- where R' is thiadiazolyl or amino thiazolyl, and a is methylene carrying oxyiimino, or R' is haloacetyl and A may also be methylene,...
US5767277 (A), filed
Tue Jan 07 00:00:00 CST 1997
, published
Tue Jun 16 00:00:00 CDT 1998
- NISSAN CHEMICAL IND LTD
An optically active beta -aminoalkoxyborane complex of the formula (I): IMAGE (I) wherein R1 is C1-C8 alkyl, C3-C7 cycloalkyl, C7-C11 aralkyl or C6-C10 aryl, R2 is hydrogen, C1-C8 alkyl, C3-C7 cycloalkyl or C7-C11 aralkyl, or R1 and R2 together form...
US7268267 (B2), filed
Wed Jun 29 00:00:00 CDT 2005
, published
Tue Sep 11 00:00:00 CDT 2007
- UOP LLC
A process for the alkylation of aromatics with olefins using a solid catalyst bed containing UZM-8 zeolite is disclosed. A polyalkylated aromatic is passed to the catalyst bed to reduce the concentration of the olefin at alkylation conditions. A portion of the...
US6576582 (B1), filed
Wed Nov 15 00:00:00 CST 1995
, published
Tue Jun 10 00:00:00 CDT 2003
- EXXONMOBIL OIL CORP
There is provided a substantially binder-free catalytic molecular sieve which has been modified by being ex situ selectivated with a silicon compound. The ex situ selectivation involves exposing the molecular sieve to at least two silicon impregnation...
US5478548 (A), filed
Fri Feb 04 00:00:00 CST 1994
, published
Tue Dec 26 00:00:00 CST 1995
Methods for synthesis of chemical compounds by catalytic transfer hydrogenation comprise forming a mixture of a starting material, a hydrogen donor material and a catalyst. The catalyst is selected from a catalytic form of carbon, a polyethylene glycol phase...
US5700938 (A), filed
Tue Jun 06 00:00:00 CDT 1995
, published
Tue Dec 23 00:00:00 CST 1997
- EISAI CO LTD
The present invention provides an industrially advantageous process for preparing a 2-alkyl-3-(biphenyl-4-yl)methyl-3H-imidazo[4,5-b]pyridine derivative represented by the following formula (II) which is a precursor of an antagonist against an angiotensin II...
US5708032 (A), filed
Tue May 23 00:00:00 CDT 1995
, published
Tue Jan 13 00:00:00 CST 1998
- MONSANTO CO
Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops, these compounds having the structure: IMAGE where Q is -(C=S)-R1 and R1 is -OR5, -SR5, halogen, -NHOH or -NR5R6. Each of R5...
US7230128 (B2), filed
Fri May 10 00:00:00 CDT 2002
, published
Tue Jun 12 00:00:00 CDT 2007
- PHILLIPS POTROLEUM COMPANY
Fluorenyl-containing metallocenes are disclosed along with methods for making the metallocenes. Also disclosed are methods for using the metallocenes as polymerization catalysts. In addition, polymers resulting from such polymerizations are disclosed.
US7288669 (B2), filed
Fri Aug 26 00:00:00 CDT 2005
, published
Tue Oct 30 00:00:00 CDT 2007
- ROHM HAAS
An improved catalyst comprising a mixed metal oxide, either promoted or not, is useful for the vapor phase oxidation of an alkane or a mixture of an alkane and an alkene to an unsaturated carboxylic acid and for the vapor phase ammoxidation of an alkane or a...
US5037917 (A), filed
Fri Jun 09 00:00:00 CDT 1989
, published
Tue Aug 06 00:00:00 CDT 1991
- DOW CHEMICAL CO
A process for preparing a polymer having perfluorocyclobutane rings by the steps of (a) contacting monomers having at least two dimerizable perfluorovinyl groups; and (b) exposing the monomers to sufficient heat and for a sufficient time that a polymer...
US5093432 (A), filed
Thu Sep 28 00:00:00 CDT 1989
, published
Tue Mar 03 00:00:00 CST 1992
- EXFLUOR RES CORP
This invention pertains to a method for liquid phase fluorination for perfluorination of a wide variety of hydrogen-containing compounds.
US4429176 (A), filed
Mon Feb 08 00:00:00 CST 1982
, published
Tue Jan 31 00:00:00 CST 1984
- MOBIL OIL CORP
A zeolite of improved stability for use in acid-catalyzed reactions is prepared by mildly presteaming the catalyst under controlled conditions of temperature, time, and steam partial pressure. The resulting catalyst retains nearly the same activity as that of...
US4158667 (A), filed
Thu Jul 28 00:00:00 CDT 1977
, published
Tue Jun 19 00:00:00 CDT 1979
- UPJOHN CO
Prostaglandin (PG1) derivatives having (1) a 6-keto feature, for example IMAGE or (2) a 9-deoxy-6,9-epoxy feature together with a 5-halo or 6-hydroxy feature, for example IMAGE or IMAGE said derivatives having pharmacological activity. Processes for...
US7449597 (B1), filed
Tue Oct 19 00:00:00 CDT 2004
, published
Tue Nov 11 00:00:00 CST 2008
- UOP LLC
A catalyst useful for carbonylation of olefins has been developed. The catalyst comprises a palladium compound, e.g. PdImSUB4/SUBClSUB2/SUB, where Im is imidazole and HCl dissolved in water or an alcohol. Carbonylation using this catalyst involves contacting...
US4647447 (A), filed
Mon Jan 23 00:00:00 CST 1984
, published
Tue Mar 03 00:00:00 CST 1987
- SCHERING AG
A diagnostic medium contains at least one physiologically well tolerated complex salt comprising an anion of a complexing acid and one or more central ion or ions of an element with an atomic number of 21 to 29, 42, 44 or 57 to 83 and, optionally, one or more...
US4352751 (A), filed
Mon Sep 10 00:00:00 CDT 1979
, published
Tue Oct 05 00:00:00 CDT 1982
- ANALYTICAL RADIATION CORP
Species-linked diamine triacetic acids of the formula IMAGE wherein T is an organic species containing at least one amine, hydroxyl, or thiol functional group, L is the residue of at least one of those functional groups and R is a two or more atom long...
US4351760 (A), filed
Fri Sep 07 00:00:00 CDT 1979
, published
Tue Sep 28 00:00:00 CDT 1982
- SYVA CO
Fluorescent antigen conjugates are provided comprising antigens covalently bonded to at least one 2,7-dialiphatic substituted-9-phenyl-6-hydroxy-3H-xanthen-3-one, wherein the 1- and 8-positions are unsubstituted. Also provided are novel fluorescent compounds...
US4544539 (A), filed
Wed May 11 00:00:00 CDT 1983
, published
Tue Oct 01 00:00:00 CDT 1985
- EXXON RESEARCH ENGINEERING CO
A zeolite related to zeolite L and having a characteristic cylindrical morphology may be prepared from a crystallization gel comprising (in mole ratios of oxides): K2O/SiO2: 0.22-0.36 H2O/K2O: 25-90 SiO2/Al2O3: 6-15 and preferably with the mole ratio...
US4329249 (A), filed
Wed Sep 27 00:00:00 CDT 1978
, published
Tue May 11 00:00:00 CDT 1982
- LUBRIZOL CORP
Nitrogen-containing phosphorus-free carboxylic acid derivatives made by reaction of an acylating agent with an alkanol tertiary monoamine are described. Typically the carboxylic acylating agent is an alkyl or alkenyl succinic anhydride containing about 20 to...
US4221810 (A), filed
Thu Mar 23 00:00:00 CST 1978
, published
Tue Sep 09 00:00:00 CDT 1980
- NISSHIN FLOUR MILLING CO
alpha -Tocopheryl derivatives, useful as agents for the treatment of ulcer, are described.
US5237110 (A), filed
Fri Feb 16 00:00:00 CST 1990
, published
Tue Aug 17 00:00:00 CDT 1993
- WISCONSIN ALUMNI RES FOUND
US4707440 (A), filed
Mon Jan 30 00:00:00 CST 1984
, published
Tue Nov 17 00:00:00 CST 1987
- ENZO BIOCHEM INC
A detectable molecule of the formula A3-(-X-R1-E-Detb)m where A3 is A2 or a polymer, where A3 has at least one modifiable reactive group selected from the group consisting of amino, hydroxy, cis OH, halides, aryl, imidazoyl, carbonyl, carboxy, thiol or a...
US7396969 (B2), filed
Thu Apr 14 00:00:00 CDT 2005
, published
Tue Jul 08 00:00:00 CDT 2008
- MOBIL OIL CORP
A process for producing alkyl aromatic compounds which comprises contacting at least one aromatic compound with at least one alkylating agent or transalkylating agent possessing at least one aliphatic group having from 1 to 5 carbon atoms under alkylation or...
US5476823 (A), filed
Fri May 28 00:00:00 CDT 1993
, published
Tue Dec 19 00:00:00 CST 1995
- MOBIL OIL CORP
An ex situ selectivated catalytic molecular sieve for enhanced shape selective hydrocarbon conversions in which a catalytic molecular sieve is modified by being exposed to at least two selectivation sequences, each sequence including an impregnation of the...
US5349090 (A), filed
Fri Feb 04 00:00:00 CST 1994
, published
Tue Sep 20 00:00:00 CDT 1994
- HOECHST CELANESE CORP
Arylketoamines are prepared by reacting arylisonitrosoalkanones with hydrogen in the presence of a transition metal catalyst and a liquid carboxylic acid at a temperature of less than about 60 DEG C.
US4746680 (A), filed
Fri Apr 19 00:00:00 CST 1985
, published
Tue May 24 00:00:00 CDT 1988
- BOOTS CO PLC
Compounds of formula I IMAGE in which R1 is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-7 cycloalkyl, cycloalkylalkyl or optionally substituted phenyl; R2 is H or C1-3 alkyl; R3 and/or R4 are H, formyl, C1-3 alkyl, C3-6 alkenyl, C3-6 alkynyl, C3-7...
US4510340 (A), filed
Fri May 20 00:00:00 CDT 1983
, published
Tue Apr 09 00:00:00 CST 1985
- INT FLAVORS FRAGRANCES INC
Described is a mixture of vinyl alkanols produced by carrying out an oxo reaction on pinene and then carrying out an oldol condensation with the reaction product. The resulting products are useful as favoring and perfumery.
US4637988 (A), filed
Mon Feb 03 00:00:00 CST 1986
, published
Tue Jan 20 00:00:00 CST 1987
- EASTMAN KODAK CO
There are described stable fluorescent labels comprising a complex of lanthanide metal and a chelating agent comprising a nucleus which is a triplet sensitizer having a triplet energy greater than that of said lanthanide metal and at least two heteroatom-conta...
