1,731 items found. Displaying 1 through 15
US5449756 (A), filed
Jul 09, 1993
, published
Sep 12, 1995
- BOEHRINGER INGELHEIM INT
The present invention is directed to recombinant the IL-21R beta chain or fragments thereof, cDNA coding therefore, vectors containing said cDNA, hosts transfected by said vectors, and monoclonal antibodies to said recombinant IL-2R beta or fragments thereof.
US5624900 (A), filed
May 09, 1994
, published
Apr 29, 1997
- KURARAY CO
Peptides having high binding activity for human interleukin-1 and represented by the following formula H-X1-Cys-A-B-A-B-A-Ser-X2-Y wherein each A represents an amino acid residue selected from the group consisting of Val, Leu, Ile and Nle, independent of any...
US6153431 (A), filed
May 28, 1998
, published
Nov 28, 2000
- FOND MONDIALE RECH PREV SIDA
The present invention relates to variants of the CCR5 human immunodeficiency virus ("HIV") co-receptor which result in a resistance of CCR5 expressing cells to HIV infection. The detection of such mutations may be used to identify individuals at lower risk for...
US6548065 (B1), filed
Dec 10, 1997
, published
Apr 15, 2003
- IMMUNEX CORP
There are disclosed Interleukin-15 Receptor (IL-15R) proteins, DNAs and expression vectors encoding IL-15R, and processes for producing IL-15R as products of recombinant cell cultures.
US6656466 (B1), filed
Jun 06, 1995
, published
Dec 02, 2003
- GENENTECH INC
The present invention relates to novel process for the preparation of glycoproteins by mammalian cell culture wherein the sialic acid content of the glycoprotein produced is controlled over a broad range of values by manipulating the cell culture environment....
US6686448 (B2), filed
May 21, 2001
, published
Feb 03, 2004
- ZYMOGENETICS INC
Novel receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise an extracellular domain of a cell-surface receptor that is expressed in kidneys, pancreas, prostate, adrenal...
US2002164785 (A1), filed
Feb 12, 2002
, published
Nov 07, 2002
The present invention provides for nucleic acid sequences that encode novel mammalian receptor polypeptides, designated OCR1. The invention also provides assay systems that may be used to detect and/or measure ligands that bind the MAMMALIAN OCR1 gene product....
US2003027253 (A1), filed
Nov 28, 2001
, published
Feb 06, 2003
Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor19, a novel class II cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferati...
US2003045683 (A1), filed
Jan 25, 2002
, published
Mar 06, 2003
- IMMUNEX CORP
DNA encoding H14 polypeptides and methods for using the encoded polypeptides are disclosed.
US2003077706 (A1), filed
Mar 04, 2002
, published
Apr 24, 2003
Cytokines and their receptors have proven usefulness in both basic research, animal models, and as therapeutics. The present invention provides a new cytokine receptor designated as "mouse Zcytor16," which can bind and antagonize the IL-TIF cytokine.
US2003096339 (A1), filed
Jun 26, 2001
, published
May 22, 2003
Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or...
US2003148447 (A1), filed
Sep 13, 2002
, published
Aug 07, 2003
- ZYMOGENETICS INC
Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zalpha11, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or...
US2003157096 (A1), filed
Aug 08, 2001
, published
Aug 21, 2003
Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for soluble zcytor11 receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate...
US2003170632 (A1), filed
Oct 26, 2001
, published
Sep 11, 2003
DNA encoding IL-1R AcP splice variant polypeptides, the polypeptides and methods for using the encoded polypeptides are disclosed.
US2003187198 (A1), filed
Mar 19, 2002
, published
Oct 02, 2003
- HYSEQ INC
The invention provides novel polynucleotides isolated from cDNA libraries of human fetal liver-spleen and fetal liver as well as polypeptides encoded by these polynucleotides. The polypeptide is a human chemokine receptor that is a member of a family of G...