29 items found. Displaying 1 through 15
US5985902 (A), filed
Feb 18, 1997
, published
Nov 16, 1999
- SEARLE CO
A class of substituted isoxazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II wherein R1 is selected from hydroxyl, lower alkyl, carboxyl, lower...
US5696143 (A), filed
Sep 20, 1994
, published
Dec 09, 1997
A class of benz[g]indazolyl derivatives is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I IMAGE (I) wherein A is -CH=CH-; wherein R1 is selected from lower...
US5028614 (A), filed
Mar 30, 1990
, published
Jul 02, 1991
- MERRELL DOW PHARMA
US5643933 (A), filed
Jun 02, 1995
, published
Jul 01, 1997
- SEARLE CO
This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation.
US7030153 (B2), filed
Dec 27, 2002
, published
Apr 18, 2006
- SEARLE CO
A class of 3,4-diaryl substituted thiophene, furan and pyrrole derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interest are...
US2003013744 (A1), filed
Jul 01, 2002
, published
Jan 16, 2003
- SEARLE CO
A class of 3,4-diaryl substituted thiophene, furan and pyrrole derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interest are...
US6274590 (B1), filed
Sep 14, 2000
, published
Aug 14, 2001
- SEARLE CO
A class of 3,4-diaryl substituted thiophene, derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interest are defined by...
US6599934 (B1), filed
Nov 13, 2000
, published
Jul 29, 2003
- SEARLE CO
A class of 3,4-diaryl substituted thiophene, furan and pyrrole derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interest are...
US6492413 (B2), filed
Mar 20, 2000
, published
Dec 10, 2002
- SEARLE CO
A class of 3,4-diaryl substituted thiophene, furan and pyrrole derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interest are...
US2003153602 (A1), filed
Dec 27, 2002
, published
Aug 14, 2003
- SEARLE CO
A class of 3,4-diaryl substituted thiophene, furan and pyrrole derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interest are...
US2004147565 (A1), filed
Jan 12, 2004
, published
Jul 29, 2004
- SEARLE CO
This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation.
US5633272 (A), filed
Jun 07, 1995
, published
May 27, 1997
A class of substituted isoxazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II IMAGE II wherein R1 is selected from hydroxyl, lower alkyl, carboxyl,...
US6677364 (B2), filed
Dec 04, 2001
, published
Jan 13, 2004
- SEARLE CO
This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation.
US2002086886 (A1), filed
Dec 04, 2001
, published
Jul 04, 2002
- SEARLE CO
This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lizoxygenase, such as inflammation.
US5668161 (A), filed
Jul 09, 1996
, published
Sep 16, 1997
- SEARLE CO
A class of substituted thiazolyl compounds is described for use in treating inflammation disorders. Compounds are defined by Formula II IMAGE II wherein R1 is selected from hydrido, alkyl, haloalkyl, cyanoalkyl, alkylamino, aralkyl, arylamino, heteroaryls...