ANTIGENS, MEANS AND METHOD FOR THE DIAGNOSIS OF LYMPHADENOPATHY AND ACQUIRED IMMUNE DEFICIENCY SYNDROME - Patent CA1275040(A1)
Filed:
Dec 19, 1983
Published:
Oct 09, 1990
Abstract
The invention concerns a newly isolated retrovirus extract obtained from a T-lymphotropic retrovirus, purified by precipitation and equilibrium uniting in a sucrose gradient, and containing a p25 protein which recognizes immunologically sera of patients afflicted with lymphadenopathy syndrom (LAS) or acquired immune deficiency syndrom (AIDS). It relates to a method and kit for in vivo assay of LAS or AIDS involving contacting sera from patients to be diagnosed for such diseases with said retrovirus extract labelled by a radioactive, enzymatic or immunofluorescent label and by detecting the immunological reaction, if any. The invention further relates to the use of the newly isolated retrovirus extract as a source of AIDS control antigen.Applicants
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PASTEUR INSTITUT
Inventors
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AXLER-BRIN CLAUDINE
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MONTAGNIER LUC
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GRUEST JACQUELINE
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REY FRANCOISE
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ROUZIOUX CHRISTINE
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CHAMARET SOLANGE
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DAUQUET CHARLES
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ROZENBAUM WILLY
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BARRE-SINOUSSI FRANCOISE
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VEZINET-BRUN FRANCOISE
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NUGEYRE MARIE-THERESE
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CHERMANN JEAN-CLAUDE
Application Number
000443605Priority Claims
FR8407151Family Members
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