Human immunodeficiency viruses associated with Acquired Immune Deficiency Syndrome (AIDS), a diagnostic method for AIDS and pre-AIDS, and a kit therefor - Patent US4708818(A)

Filed: Oct 08, 1985

Published: Nov 24, 1987

Abstract

Retroviruses associated with Acquired Immune Deficiency Syndrome (AIDS), including Lymphadenopathy Associated Virus (LAV), are isolated from the sera of patients afflicted with Lymphadenopathy Syndrome (LAS) or AIDS. LAV is a Human Immunodeficiency Virus (HIV). Viral extract, structural proteins and other fractions of the retrovirus immunologically recognize the sera of such patients. Immunological reaction is used to detect antibodies that specifically bind to antigenic sites of the retrovirus in samples of body fluids from patients with AIDS or risk of AIDS. A kit for in vitro assay of LAS or AIDS is provided.

Applicants

US HEALTH
PASTEUR INSTITUT

Inventors

AXLER-BLIN CLAUDINE
GRUEST JACQUELINE
MONTAGNIER LUC
POPOVIC MIKULAS
BRUN-VEZINET FRANCOISE
ROUZIOUX CHRISTINE
SARNGADHARAN MANGALASSERIL G
REY FRANCOISE
DAUGUET CHARLES
CHAMARET SOLANGE
GALLO ROBERT C
ROZENBAUM WILLY
BARRE-SINOUSSI FRANCOISE
CHERMANN JEAN-CLAUDE
NUGEYRE MARIE-THERESE

Application Number

785638

Priority Claims

FR8407151

Family Members

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Classification Codes

A61K39/00, C12N15/09, G01N33/569, C07K14/155, A61K35/76, C12N5/10, C12R1/92, A61P31/12, A61K35/12, A61P31/18, A61K39/21, A61K35/28, C07K14/195, C12N7/02, C07K14/05, C12Q1/70, C07K14/16, A61K35/66, C12N7/00, A61P31/00