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Process for producing antibodies to hepatitis virus and cell lines therefor - Patent US4271145(A)

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Filed: Oct 22, 1979
Published: Jun 02, 1981

Abstract

Cell lines for producing monoclonal antibodies to hepatitis virus are established by immunizing animal lymphocytes with hepatitis antigen to form antibody producing cells which then are fused with myeloma cells. The resultant somatic cell hybrids can be cloned. These clones produce monoclonal antibodies to individual antigenic determinates unique to hepatitis virus.

Applicants

  • MASSACHUSETTS GEN HOSPITAL

Inventors

  • ZURAWSKI JR VINCENT R
  • WANDS JACK R

Application Number

086947

Priority Claims

US8694779

Family Members

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Classification Codes

G01N33/576, C12N5/10, A61K39/395, C07K16/08, C12R1/91, C12N15/02, C12P21/08
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